The finer details are lost when this image is displayed using chroma subsampling. This can be dangerous in mission-critical environments where key decisions are made based on the presented data. When sampling text at 4:2:2 or 4:2:0, then the quality will drop making said text increasingly difficult to read.
When choosing products for video walls, for example, it's crucial to choose technologies that allow versatility with regards to color space. Take a control room for instance. Part of the control room wall may display charts or graphs where every detail matters. In this case, a capture, encoding, decoding, and display product which has the capability to handle 4:4:4 is better suited. On the other hand, if watching a feed of high motion content, say a sports event, then the overall network bandwidth could be reduced by having this video play at 4:2:0. Versatility is key when choosing products for capture, streaming, recording, decoding, and display as it allows the user to reach a wider range of functionality.
While the output image will look very similar, and the bandwidth required to transfer the image will be the same2, the storage and transfer of data will differ between the two.
RGB will transmit content with a predetermined color depth per component. This means that each of the R, G, and B will contain data for each of the red, green, and blue color components respectively to collectively formulate the overall color of each pixel.
YUV, on the other hand, will transmit each pixel with the associated luma component, and two chroma components.