Immune Suppression in Lyme Disease
Most with chronic Lyme disease have immune suppression that makes it hard to recover. There are many issues that effect the immune system including:
- infection toxins and factors,
- hygiene like diet and rest,
- hormones,
- emotional toxins,
- environmental toxins, and
- excess inflammatory cytokines.
In this article I describe each of these factors and steps to change them. I lay out a step-by-step approach for life style changes and supplements that boost or support the immune system.
Healthy Immune Hygiene in a Lyme Disease Treatment
One of the best ways to optimize the immune system is through regular immune boosting practices. These include light to moderate exercise, meditation, quality sleep, and a healthy diet. For information about sleep see: Sleep 101: The Basics. For information about diet see The Best Brain, Inflammation, Pain, and Detox Diet Ever.
Although exercise is generally good, if done in excess it too can suppress the immune system. So exercise to tolerance only. Experiment to see what amount and intensity of exercise does not leave you more tired or in pain the next day. For some in the beginning of treatment any amount of exercise is too much.
Support for the immune system starts by providing the building blocks it needs which are free of environmental toxins. A diet rich in whole (non-processed) organic foods provides essential micronutrients for immune function and optimal liver and kidney detoxification. However, a healthy diet alone does not provide adequate levels of essential micronutrients for those with chronic Lyme disease. Compared to the past, the earth is less micronutrient dense. For this reason a well balancedmultivitaminwith minerals plus amino acids is essential.
Emotional Toxins
Of all the toxins, emotional stress is the most poisonous. The emotional stress of this illness is difficult. In addition many have histories of sexual or emotional abuse and trauma that is unresolved. In some instances I have seen effective counseling as the factor that leads to major health improvement. If these are your issues get the help of a counselor.It could be the thing that most changes your health.
Cytokines
Cytokines are made when immune cells are stimulated by germs, oxidizing agents, cytokines, toxins, and other agents. These inflammatory agents stimulate white blood cell production and improve white blood cell function to fight infections.However, in Lyme disease too may are made.Excess cytokines cause many problems. This includes suppression of the immune system. Read much more information about cytokines.
Hormones
Low thyroid and adrenals are common in chronic Lyme disease. Both of these hormones help the immune system run effectively. Readandfor more information about this topic.
EnvironmentalToxins
Many things in the environment suppress the immune system. These include pesticides, insecticides, heavy metals, and poor quality air and water. Emotional and biologic toxins also suppress the immune system. SeeDetoxification 101: The Basicsfor more information on how to deal with toxins.
Infections
For information on treating infections see the chapter Infection Treatment Plans for Lyme Disease.In my experience from when I practiced in Seattle, it is best to focus initially on treating
- Lyme (borrelia),
- babesia,
- bartonella, and
- intestinal yeast overgrowth.
Other infections like the chronic viruses will often get better as the immune system is able to deal with them more effectively after these infections are treated and the other basic recommendations below are put in place.
Supplements
Here is a list of supplements that may help.
- Curcumin, a component of turmeric, is an antioxidant that works at the cellular level through a variety of mechanisms to block cytokine production. Liposomal products, where the curcumin is microscopically wrapped in fat to increase absorption, seem to work best.
- Thymic protein Aboosts cell-mediated immunity. This is a refined thymus gland protein that turns on T-4 white blood cells and increases the immune system's ability to fight acute and chronic infection.
- Astragalus complexorolive leaf extractstimulate and modulate the immune system for those with chronic infections and long term immune dysfunction. Both are anti-oxidants.
- Olive leaf extractalso has direct anti-microbial properties.
- Transfer Factorsturn on components of cell mediated-immunity. ReadTransfer Factors: Turn on The Armyfor more information including which transfer factor product to use depending on the infections you have.General transfer factorsturn on a group of cell-mediated immunity cells called natural killer cells. When turned on these cells help fight a variety of bacterial and virus infections.Targeted transfer factorsfor chronic Lyme and associated diseases turn on the cell-mediated immune response for specific infections that can occur in chronic Lyme and associated diseases. These infections are borrelia (the Lyme disease germ), bartonella, and babesia. In addition targeted transfer factors effect the cell-mediated immune response against HHV-6, EBV, and CMV virus infections. These are viruses found in most healthy people that are kept under control by the cell-mediated part of the immune system. In individuals with chronic Lyme disease these viruses can become more active.
- Medicinal Mushroomsalso turn on cell mediated-immunity against viruses and bacteria. A multi-variety mushroom mix works which workseffectively against bacteria and viral infections. A multi-variety mix shouldinclude:maitake,reishi gano,sh*take,agaricus blazei, andcoriolus vericolormushroom extracts. Reishi gano mushrooms used alone are best for repeat chronic or repeat viral infections.
- Multivitaminwith minerals, antioxidants, b-complex,and amino acids replaces essential nutrients lacking in most diets.
Immune System Treatments in Lyme
Consider the recommendations above about:
- healthy immune hygiene
- emotional toxins
- cytokines
- hormones
- environmental toxins, and
- infections.
Take the multivitamin and curcumin.
- Multivitamin. I preferpowderproducts made by Integrative Therapeutics or by Thorne that include minerals, b complex, antioxidants, and amino-acids.
- Curcumin 500 mg.1 to 2 pills 3 times a day. Use aliposomal curcumin for best absorption.
Beginning of Treatment
Start either general transfer factors or the multi-variety mushroom mix. Consider doing this especially if there is a history of repeat colds and other viral infections prior to beginning treatment.
- General Transfer Factors.Use a Transfer Factor Multi-Immune complex 2 pills 1 time a day without food (do not take beginning 30 min before eating through 2 hours after eating.) Transfer Factor Multi-Immune by Researched Nutritionals is an example of one general transfer factor product.
- Multi-variety Mushroom Mix.1 to 2 pills 3 times a day. Be sure the mix includesmaitake,reishi gano,sh*take,agaricus blazei, andcoriolus vericolormushroom extracts. Immune Builder 5 Mushroom Formula by JHS Naturals is an example of a mult-variety mushroom mix.
For information about chronic virus infections like HHV-6, EBV, or CMV infections and a full treatment approach seeKills Viruses: A Brief Guide.For immune support during the chronic viral infection treatment use both reishi mushrooms, thymic protein A, and targeted transfer factors for viruses
- Reishi Mushrooms.1 to 3 pills 3 times a day.
- Thymic Protien A.1 package under tongue away from food 3 times each day for 2 days at the onset of any acute viral infection then 1 packet daily.
- Targeted Transfer Factors.1 pill daily for 7 days, then 1 pill 2 times a day without food (do not take beginning 30 min before eating through 2 hours after eating). The targeted transfer factor mix should include transfer factors for various viruses. One product that does this isTransfer Factor Plasmycby Researched Nutritionals.
Borrelia, Bartonella, Babesia, HHV-6, EBV, and CMV
When treatment for borrelia, bartonella or babesia is going poorly after 6 months of treatment add targeted transfer factors. If babesia, bartonella, or borrelia relapse, then add targeted transfer factors and remain on them once the anti-microbials are stopped.
- Targeted Transfer Factors.1 pill daily for 7 days, then 1 pill 2 times a day without food (do not take beginning 30 min before eating through 2 hours after eating). The targeted transfer factor mix should include transfer factors for borrelia, bartonella, babesia, cmv, hhv-6 and ebv. One product that does this is Transfer Factor L Plusby Researched Nutritionals.
Repeat Viral Infections
For repeated viral infections like colds and the flu, then add Thymic Protein A and Astragulus Complex. If this does not help then add olive leaf extract.
- Thymic Protein A.1 package under tongue away from food 3 times each day for 2 days at the onset of any acute viral infection then 1 packet daily.
- Astragalus complex. 2 pills in morning and 2 pills in the afternoon.
- Olive leaf extract 500mg.1 pill 2 times each day with food.
- Anthocyannins.1 tsp 3-6 times each day in 8 oz water.
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