Does MK 677 increase testosterone? What You Should Know. (2023)

Does MK 677 increase testosterone? In the SARM universe, there’s plenty of jargon, and many concepts that are similar to each other. They kind of clash against each other like various parts of a weight machine. For example, is a SARM a type of steroid?

What’s the difference? Is HGH the same as testosterone? What does HGH (human growth hormone) have to do with SARMs? Is MK-677 a SARM? Is it something directly tied to testosterone levels? Do you take it if you have low T?

Does MK 677 increase testosterone? What You Should Know. (1)

Well, just like you may find yourself showing some newbies around the gym (“what does this machine do?” What about that one?”) and keeping them from hurting themselves, we’ll take on the role of mentor and help you hack through the jungle of terms on this issue.

Basically, we’ll show how MK-677 really has nothing to do with testosterone, and if you’re interested in the work of that hormone on the body, we’ll walk you through that too.

First, What’s MK-677?

Say your friends are getting banging results from taking MK-677. They’ve described it to you and it sounds like a SARM (selective androgen receptor modulator). How is it different? Does it have the same side effects of SARMs?

Does MK 677 increase testosterone? What You Should Know. (2)

OK, MK-677 is not a SARM. It’s actually a growth hormone secretagogue, which means it acts on the body’s glands to induce secretions of growth hormone (HGH). So, you see: it’s not a SARM and it’s not HGH, it just makes your body produce more HGH.

Your gym-rat friends have gotten buff with MK-677 because of the increase in growth hormone. Growth hormone makes a weight lifter recover faster from a workout. It injects you with energy, and in addition, aids in restful sleep.

Does MK 677 increase testosterone? What You Should Know. (3)

Those are the reasons people are attracted to MK-677. As you can already see, we’re not talking about an increase in testosterone here.

(Video) Greg Doucette IFBB PRO MK-677 EXPLAINED.

You Mean It Does Increase Testosterone?

In a word: no. No it does not. But let’s not leave a bud hanging–we’ll explain in full.

Does MK 677 increase testosterone? What You Should Know. (4)

Testosterone Defined

Testosterone is a sex hormone (not an ab crunch hormone). It is responsible for the development of the testicles and the penis, as well as body hair and the deep voice that dudes tend to have.

Yes, it does lead to muscle growth, which is why men have larger muscles than women. Testosterone is regulated and sent to throughout the body by the pituitary gland.

Testosterone vs. Human Growth Hormone

First off, when we talk about HGH we mean the hormone inside of a person, not supplements of it. Human Growth Hormone is what’s known as a proteohormone. It comes from the pituitary gland and is very important in stimulating the insulin-like growth factor to lead a child through their crucial growth.

But it’s important for adults too, or else it wouldn’t help bodybuilders. Anyway, while HGH comes from the same gland as testosterone, it is quite different. There is no connection between the two, and MK-677 has no effect whatsoever on testosterone.

Does MK 677 Increase Testosterone: How Do You Increase Testosterone?

Does MK 677 increase testosterone? What You Should Know. (5)

Perhaps you’re here worried about your testosterone level. Don’t be discouraged about the fact that MK-677 (ibutamoren) neither increases nor decreases testosterone. There are plenty of ways to increase testosterone in a healthy way, whether you’re trying to gain lean muscle mass or improve your body composition in some way.

Increase your sleep

Studies have shown that too little sleep reduces testosterone levels.

Eat good fats

Sure, we tend to believe that dietary fat is bad. But that’s because many fat-bearing foods are deep-fried or filled with too much saturated fat.

(Video) MK-677 Better Than HGH? Benefits, Side Effects, Dosage & What To Expect

But when it comes to testosterone, studies have shown that a diet higher (as opposed to lower) in various fats, particularly monounsaturated and healthy unsaturated fats causes an increase in testosterone.

Now, some of the foods that you’ve heard of as being “healthy fats” are indeed the ones carrying healthy monounsaturated fats: peanut butter, olive oil, walnuts, avocados.

Devour cauliflower

When you eat cauliflower (a low glycemic replacement for potatoes) your body produces DIM (diindolymethane), which is an engine of testosterone production.

Does MK 677 increase testosterone? What You Should Know. (6)

Do cardio work

You may wish to carve out some sick muscles, and that’s fine. But don’t forget the cardio. Here’s a clinical trial demonstrating that cardio workouts help testosterone levels.

The cool thing about all of these methods is that they’re not difficult at all, they don’t change your lifestyle or put you out, and you’re probably already doing some of them to some extent.

How Do You Increase HGH Naturally?

And does that mean you’re about to receive a basic overview of testosterone?

Fast sporadically

Doing brief fasts will absolutely raise HGH levels. You could go with a plan that caps calories over a period, such as 700-800 per week. Another plan could be something like having an 8-hour eating window with 16-hour fasting. This helps you drop body fat and keeps insulin down, and both of these boost HGH.

Eat less sugar

This is another great solution because it’s something that you should do anyway. Reducing your sugar intake will help you with all the fitness goals you have. People with lower blood sugar have higher HGH levels.


GABA supplement

GABA is a natural supplement, short for Gamma aminobutyric acid, which is an important neurotransmitter. It is known to increase HGH.

Does MK 677 increase testosterone? What You Should Know. (7)

High intensity exercise

The workout regimen you are using to meet your goals can actually increase HGH. As you know, high intensity exercises include sprints, circuit training and high-intensity interval training.

The body responds to the intensity of exercise by trying to replace any muscles that may be torn and generally to re-establish equilibrium. When you do high-intensity workouts, you’ll get a spike of HGH, but any type of exercise is good.

Does MK-677 Have Side Effects?

As we’ve seen, MK-677 has many benefits for any user. It’s also true that MK-677 doesn’t increase testosterone and also doesn’t decrease it. However, if you’re thinking of using any supplement, no matter how natural it is, it’s important to be aware of side effects it may have.

There are a few mild side effects associated with MK-677. We’ll give you the rundown on a few of them and describe how serious or not they are.

Increased blood sugar

According to this study, MK-677 is sometimes associated with an increase in blood sugar. However, it’s very important to understand that, contrary to some rumors, MK-677 doesn’t cause insulin resistance.


The work of MK-677 can sometimes cause certain nerves to feel pressure. This can cause a tingling or even a numbness in hands. This will almost certainly go away before the end of your cycle.

Increased appetite

it’s true that a person does experience a bigger appetite while using MK-677. Ghrelin, the hormone activated by MK-677, increases people’s appetites. If you consider this a side effect, then put it on the list. But if you choose your proteins carefully and keep the sodium low, you can use your food intake for increased lean body mass.

(Video) MK677 First Cycle What To Expect

Mythical Side Effects

Does MK 677 increase testosterone? What You Should Know. (8)

There are many stories of what’s happening while using MK-677. Some “side effects” of MK-677 are things that may happen during MK-677 use, but aren’t in fact caused by it. Post Hoc Ergo Propter Hoc anyone?

Here are a few examples.


Some people think bloating can be caused by MK-677. Yet, there have to be things other than MK-677 in play for this bloating to happen. Sometimes abdominal bloat comes from water retention. The water retention, in turn, can be caused by high-carb or high-sodium foods.

Joint Pain

Some people may think that users of MK-677 experience joint pain. In fact, some folks may indeed have joint pain while using MK-677. It’s not that hard to realize that people who are trying to beef up may do the kind of max outs that lead to joint pain.

In fact, clinical trials, like this one, for example, have shown that grhelin, the hormone promoted by MK 677, is actually good for joint pain.

Does MK 677 Increase Testosterone: Conclusion

The important takeaway is that human growth hormone and testosterone are separate. You can take testosterone supplements while taking MK-677, if you so choose. Taking MK-677 won’t either increase or decrease testosterone.

Medical Advice Disclaimer

I’m not a doctor and neither are you. The solid research we are giving you is just that, research. It is not official medical advice.

FAQ – Does MK 677 Increase Testosterone

Q. Does ibutamoren increase testosterone?

OK, you somehow missed out on the entire article. No problem. Ibutamoren–the same thing as MK-677, does not increase testosterone. It increases HGH (human growth hormone) and that is how it helps an increase in muscle. This is separate from testosterone.

(Video) MK677 Better & Cheaper Than Growth Hormone 💪

Q. Does MK 677 affect hormones?

Absolutely! That’s what it’s all about. It is an orally active growth hormone that stimulates the hormone ghrelin to produce HGH. At the same time, the hormone causes an increase in hunger. That is why bodybuilders use it to bulk up. It’s not really about weight loss.

Q. Does MK 677 increase growth hormone?

Yes! Yes indeed. That is precisely the whole point of it. It stimulates the pituitary gland to secrete a hormone called ghrelin, which in turn spins out more HGH.

Tags: bone density, growth hormone levels, growth hormone deficiency, growth hormones, growth hormone releasing hormone, increase lean body mass, lean muscle mass growth, testosterone replacement therapy, growth hormone secretion, growth hormone release


Does MK-677 boost testosterone? ›

No. As MK-677 increases your natural growth hormone, it does not affect other hormone levels like testosterone.

Does MK-677 decrease testosterone? ›

MK-677 treatment reduced serum total testosterone (P < 0.05 vs. placebo) although total testosterone/sex hormone-binding globulin (SHBG) ratio (an index of free testosterone) was not changed.

Does MK-677 affect hormones? ›

MK-677 increases the production levels of growth factor IGF1 and growth hormone to a rate reaching up to fourty percent ( 40%). However, this is extremely valuable in cutting cycles, as it helps increase the body's Basal Metabolic Rate (BMR), enhancing the metabolism of fats for producing beneficial energy.

Does MK-677 increase bone size? ›

In 187 elderly adults (65 years or older), ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover in multiple studies. In one study with 292 post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.

Does Ibutamoren affect testosterone? ›

Ibutamoren treatment did not affect FSH and LH levels, but did lead to decreased total testosterone levels with conserved free testosterone levels.

Can you take MK-677 long term? ›

Multiple controlled studies have revealed that long term use of MK677 shows significant improvements in bone mineral density. Bone density is critical for bone health in men, the elderly, and the obese. In repeated studies, Ibutamoren consistently increased and maintained bone density.

Is MK-677 a steroid? ›

What is Ibutamoren? Ibutamoren supports the release of the growth hormone while influencing the levels of insulin-like growth factor 1 (IGF-1). It is a stimulant that improves the efficiency of muscle repair and instigates a fat loss momentum. Now the drug is neither an anabolic steroid nor a SARM.

Does MK-677 cause hair loss? ›

MK677 – Ibutamoren

It is actually a growth secretagogue, this means that it promotes the production of growth hormone in your body. This means that not only does MK677 NOT cause hair loss, but it is also a very common compound that people take to prevent hair loss from happening.

How long should a MK-677 cycle be? ›

We suggest you take Ibutamoren 25mg for about a 16 to 20-week cycle. After that take a break for at least 5 weeks. This cycle is followed by many users and they experience good results without any side effects. Many studies and research were done and they found good results around this cycle length.

How quickly does MK-677 work? ›

MK 677 before and after results

In the first two weeks, you can expect to notice the increased sleep quality benefit as well as the increase in hair and skin quality. Around the same time, you will also notice that your hair and nails are growing faster.

What are the negative effects of MK-677? ›

Reported side effects include increased appetite, swelling, anxiety, numbness and muscle pain. It also causes bone mineral density to decrease and causes increased fasting blood glucose and decreased insulin sensitivity.

How much MK-677 should you take? ›

The great thing about Ibutamoren is the fact that its very well tolerated, even in high dosages and for lengthy periods of time. The most common dosages used in studies and human trials were between 10 to 50mgs per day, with the median average and most frequently used dosage being 25mgs per day.

Does MK-677 affect brain? ›

Since MK-677 possesses many of the same properties as Ghrelin and attaches to its receptors, it is anticipated that MK-677 may have the same effects on the brain as Ghrelin. However, no research has shown that MK 677 exerts direct nootropic effects on the brain.

Do you need a PCT for MK-677? ›

Does Ibutamoren MK 677 require a PCT? No. A PCT (post-cycle therapy) is necessary after a cycle of steroids or SARMs because both types of drug suppress your ability to produce testosterone. Ibutamoren does not do this so there is no requirement for a PCT.

How much is MK-677 per day? ›

The best dosage for MK 677 when looking to gain muscle mass and lose body fat is between 20-25mg per day. Some users have reported better results at higher doses of around the 25mg range buta higher dosage will also tend to exhibit more pronounced appetite and lethargy.

What is MK-677 prescribed for? ›

Ibutamoren, or MK-677, is an oral medication that combats muscle wasting by boosting the body's natural ability to secrete human growth hormone (HGH). Ibutamoren stimulates an increase in growth hormone levels by mimicking the action of the hormone ghrelin and binding to ghrelin receptors in the brain.

Does MK-677 increase collagen? ›

Markers of bone resorption were induced within 2 weeks of treatment with MK-677; serum levels of the carboxy-terminal cross-linked telopeptide of type I collagen were increased 26% at 8 weeks (p = 0.001 vs.

Does MK-677 increase bone density? ›

MK-677 increased markers of bone formation; a 23% increase in the carboxy-terminal propeptide of type I procollagen levels and a 28% increase in procollagen III peptide levels were seen with as little as 2 weeks of MK-677 treatment (p < 0.01 and p = 0.001 vs.

Which SARM is safest? ›

Which is the safest SARM and why? If we can refer to SARMs with a term like “safe”, then we would say that the safest is LGD-4033 (Ligandrol) from Ligand Pharmaceuticals, due to several studies conducted (compared to other SARMs not yet been tested in humans at all).

Does MK-677 grow hair faster? ›

To start off, MK-677 increases IGF-1 production by 60,1% in just six weeks, according to a double-blind, placebo-controlled study.

Does MK-677 affect hair growth? ›

MK-677 elevates levels of IGF-1

A 2018 study found clinical evidence that IGF-1 does affect hair growth and alopecia.

Does HGH grow hair back? ›

In some cases, HGH or human growth hormone therapy has been an effective method of restoring and maintaining hair growth. For some HGH therapy has effectively restore hair loss and skin elasticity while reducing wrinkles and improving energy restoration.

Is MK-677 powerful? ›

Ibutamoren MK-677 is a new supplement that has been shown to be far more effective than other growth hormone releasers like HGH or GHRP-6. It's also safer than anabolic steroids, making it a good choice for those who want to see significant gains in muscle mass and strength without the risk of serious side effects.

How much weight will you gain on MK-677? ›

Weight Gain

MK-677 makes you ravenous when it comes to food, and many ectomorphs could benefit from imbuing this compound as it's so easy to put on weight while on it. I've gained around 10 pounds while on MK-677. Admittedly, some of it was from the water retention experienced, but it was nothing serious.

When should I take ibutamoren? ›

Increased sleep quality benefit is really great. In fact, some bodybuilders take this compound only because of the enhanced sleep. You will be fully rested in 6 hours because of how deep you will be sleeping. Taking your MK 677 dosage about 10-15 minutes before going to bed really makes this benefit stand out.

Does MK-677 raise blood sugar? ›

MK-677 produced significant increases in fasting glucose (5.4 +/- 0.3 to 6.8 +/- 0.4 mmol/L at 4 weeks; P < 0.01 vs. baseline) and IGF-binding protein-3. Circulating cortisol concentrations did not change, and PRL concentrations increased 23%, but remained within the normal range.

How long is ibutamoren detectable? ›

The glucuronic acid conjugated analogs of ibutamoren were detected during phase II of the study, but no sulfonic acid conjugated analogs were observed. The major metabolites can be detected up to 96 hours after a single dose, and ibutamoren can persist for up to 72 hours.

Does MK 2866 increase testosterone? ›

Yes, MK 2866 has been found to create a fat-loss momentum by enhancing the levels of testosterone in the body. In addition to lowering and controlling the fat percentage, it equally promotes muscle growth and hence, expands size.

Does MK-677 cause water retention? ›

Conclusion. In conclusion, MK 677 water retention is not something to be concerned about. It can definitely happen but if you are drinking enough water (at least 2.5 liters a day) and you have a moderately clean diet, it almost certainly won't happen to you.

Does MK-677 increase dopamine? ›

Local administration of the ghrelin receptor agonist MK0677 into the ventral tegmental area significantly increases food intake and it also significantly increased dopamine release in the nucleus accumbens, the medial prefrontal cortex and the amygdala.

Does MK-677 cause aggression? ›

MK-677 is Safe for Women

Ibutamoren is fine to use for both men and women as it doesn't affect the amount of testosterone or estrogen the body produces. This means that there is zero-risk of specific hormonal imbalances and unwanted side-effects like puffy nipples, heightened aggression or hair loss.

Can you take MK-677 with food? ›

Take all MK-677 doses in the morning and evening after eating, what is the best time to take ostarine. Take it just 1-2 days per week without stopping, mk-677 dosage in ml. Some people prefer to take it on an empty stomach after eating rather than before. They do not see any changes, mk-677 dosage.

What is MK steroid? ›

MK-0773, also known as PF-05314882, is a steroidal, orally active selective androgen receptor modulator (SARM) that was under development by Merck and GTx for the treatment of sarcopenia (loss of muscle mass) in women and men.

What is the half life of MK-677? ›

MK 677 (Ibutamoren) has a half-life of 24 hours, meaning dosing once a day will be sufficient.

Does ibutamoren increase height? ›

But if you are younger and your growth plates are still open, Ibutamoren will provide you with another growth spurt and you will be able to grow taller. You can expect to start growing after about 6 months of MK 677 (considering your growth plates are still open).

Does MK-677 increase prolactin? ›

Prolactin effects

Another potential issue with taking higher doses of MK-677 is it's impact on prolactin. This hormone is usually known for promoting breast milk in women. But, it can cause a drop in testosterone and estrogen levels, depress the immune system, and may affect mood.

Does ibutamoren make you hungry? ›

Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Is ibutamoren legal? ›

It is illegal for supplements containing ibutamoren to be supplied by supplement stores. It is also illegal for consumers to possess these products without a prescription.


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